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Medellin Salas, Brenda

Brenda P Medellin

Graduate Research Assistant I study protein function from a biophysical and structural perspective.


  • BS Chemistry, bacteriology and parasitology, Universidad Autonoma de Nuevo Leon (UANL), Monterrey, Nuevo Leon, Mexico (2012)



  • Burkholder, N.T.,Medellin, B.P., Irani, S., Matthews, W.L., Showalter, S.A.,and Zhang, Y. J. (2018). Chemical tools for studying the impact of cis/trans prolyl isomerization on RNA polymerase II CTD phosphatase activity and specificity. Methods in Enzymology. 607; 269-297.
  • LeVieux, J.A.,Medellin, B. (co-first author), Johnson, W.H. Jr., Erwin, K.,Li, W., Johnson, I.A., Zhang, Y. J.*, Whitman, C.P.* (2018).*co-corresponding author
    Structural Characterization of the Hydratase-Aldolases, NahE and PhdJ: Implications for the Specificity, Catalysis, and N-Acetylneuraminate Lyase Subgroup of the Aldolase Superfamily. Biochemistry. 57, 25, 3524-3536 doi:10.1021/acs.biochem.8b00532.
  • Gibbs, E.B., Lu, F.B., Fisher, M.J., Medellin, B.P., Laremore, T.N., Zhang, Y. J., Gilmour, D.S.,and Showalter, S.A. (2017). Phosphorylation Induces Sequence-Specific Conformational Switches in the RNA Polymerase II C-Terminal Domain. Nature Communications. 8,15233. doi:10.1038/ncomms15233